Genetic disruption of serine biosynthesis is a key driver of macular telangiectasia type 2 aetiology and progression.

Genome Med · 2021 · PMC7945323 · PMID 33750426

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

nominally significantp = 1.69e−7actually significant

SNP rs36259 is an exonic non-synonymous SNP located in the CERS4 gene which achieved close to genome-wide significance ( p = 6.270e−08) and was nominally significant in our original study ( p = 1.69e−7).

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borderline significantno p-value reported

Alanine PRS was borderline significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.