Examining the AD-DS samples and normalizing to β-actin, the AD-DS and C/AD-DS samples taken together showed a trend to a positive correlation between fl-APP and KIF5B and KIF5C (Supplemental Table 4 A).
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Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport.
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