Impact of a Mortality Prediction Rule for Organizing and Guiding Antimicrobial Stewardship Program Activities.

The ITS analyses confirmed a significant trend in the decrease of intravenous (IV) vancomycin utilization ( P = .012) ( Appendix Figure 3 ); however, despite overall reductions, there were no significant decreases in slopes of any additional antimicrobial category, including total antimicrobial ( Figure 2 ) and fluoroquinolone utilization ( P = .709) ( Appendix Figure 4 ).

also in 9,775 other papers

There was no difference in overall HO-CDI (2.6% vs 2.2%; P = .43) between cohorts; however, the ITS analysis showed a significant change in the slope of HO-CDI per 10 000 patient days ( P = .032), because the preintervention cohort showed an increasing trend in HO-CDI, whereas the postintervention cohort showed a decreasing trend ( Figure 1 ).

also in 47,180 other papers