This study revealed a strong trend of decreasing osmotic stability as cells progressed in vitro from majority basophilic and polychromatic normoblasts at day 9 (Lysis 50 73.8 ± 3.6) to a majority polychromatic and orthochromatic normoblast population at day 11 (Lysis 50 102.7 ± 15.6), and then further decreased as cells progressed through final orthochromatic normoblast maturation occurring between day 14 (Lysis 50 102.2 ± 2.0) day 17 (Lysis 50 126.2 ± 11.2), and day 20 (Lysis 50 143.4 ± 15.1) (Fig. 2d ).
1
—
—