Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors.

Cell Death Dis · 2021 · PMC7955127 · PMID 33712556

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failed to reach statistical significanceno p-value reported

In the 134111 (CCNE1 58x amplification), there was a trend towards improved outcome with WEHI-7326 treatment, however, due to individual outliers in the treatment arm, this failed to reach statistical significance.

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