Blocking Aerobic Glycolysis by Targeting Pyruvate Dehydrogenase Kinase in Combination with EGFR TKI and Ionizing Radiation Increases Therapeutic Effect in Non-Small Cell Lung Cancer Cells.

Cancers (Basel) · 2021 · PMC7956357 · PMID 33668151

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Moreover, the tumor mRNA expression of glutathione S-reductase (GSR) and superoxide dismutase 1 (SOD1) showed a trend of increase, whereas catalase (CAT) was significantly downregulated.

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