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Signaling Pathways That Control Apoptosis in Prostate Cancer.

Cancers (Basel) · 2021 · PMC7956765 · PMID 33668112

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An analysis of apoptosis by counting the percent of TUNEL positive cells in the ventral prostate gland of mice with BAX knockout ( Bax -/- ) showed significantly less apoptosis on day 5 post-castration as compared to wild-type mice, instead, a higher percent of TUNEL positive cells was detected in Bax -/- mice on day 1 and day 14 (although the difference did not reach statistical significance).

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