Integrated Bioinformatic Analysis of SARS-CoV-2 Infection Related Genes ACE2, BSG and TMPRSS2 in Aerodigestive Cancers.

The comparative analysis between metastases and related normal tissues (the lung or liver) showed that ACE2 was expressed at a higher level in lung metastasis than in normal lung tissue, whereas the difference between liver metastasis and normal liver tissue did not reach statistical significance ( Figure 7G ); liver metastases expressed BSG at a higher level than normal liver ( Figure 7H ); although TMPRSS2 expression in liver/lung metastases was higher than that in matched normal liver/lung, the differences did not reach statistical significance ( Figure 7I ).

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