Quantitative Proteomics Reveals Changes Induced by TIMP-3 on Cell Membrane Composition and Novel Metalloprotease Substrates.

Immunoblotting showed that both TIMP-3 and marimastat did not prevent CADM1 shedding under these experimental conditions ( Figure 2 and Figure 4 ), and its decrease on the cell membrane did not reach statistical significance ( Figure 3 ).

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