Consensus on DEfinition of Food Allergy SEverity (DEFASE) an integrated mixed methods systematic review.

In another study, the frequency of severe ARs compared with moderate, mild, or no ARs was 10-fold higher in asthmatic children but did not reach statistical significance (OR, 10.19; 95% CI, 1.13–91.54; P .022). 22 One study evaluated the concomitant use of drugs ie, ACE inhibitor and β-blocker) but no correlation with symptom severity was found. 26 Three studies evaluated the role of recurrence of ARs as a predictor.

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