The Current Role of Adjuvant Chemotherapy in Locally Advanced Nasopharyngeal Carcinoma.

Front Oncol · 2020 · PMC7970762 · PMID 33747895

Europe PMC DOI

hedged sentences

0.0160

closest p · 0.3× alpha

0.0520

boldest claim

The sentences

did not reach statistical significanceP =0.016actually significant

When the PF and PX induction regimens were combined for evaluation of the IC + CCRT group versus the CCRT + AC group, unadjusted comparisons did not reach statistical significance, but adjusted comparisons indicated a reduction in the hazards of disease progression (HR, 0.67; 95% CI, 0.48–0.93; P =0.016) and death (HR, 0.57; 95% CI, 0.39–0.86; P =0.006) ( 37 ).

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marginally significantP =0.052so close (0.05 < p ≤ 0.1)

A stratified analysis of tumor clinical stage indicated that the curative effect of CCRT+AC on patients with N 2–3 disease was marginally significant (HR=0.35, 95% CI=0.11–1.06, P =0.052).

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borderline significantno p-value reported

observed a borderline significant difference in OS favoring CCRT+AC treatment in patients with N2–3 disease.

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