Correlation of Frontal Atrophy and CSF Tau Levels With Neuropsychiatric Symptoms in Patients With Cognitive Impairment: A Memory Clinic Experience.

Front Aging Neurosci · 2021 · PMC7973017 · PMID 33746732

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a positive trendno p-value reported

On the other hand, the finding of a positive trend in our subjects with MCI appears to be consistent with the evidence present in the literature related to early disease stages.

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a negative trendno p-value reported

The CSF biomarkers analysis showed a negative trend of t -tau when plotted with total NPI scores in patients with primary dementias, and a positive relationship in patients with MCI, drawing a parabolic trajectory across disease stages of increasing severity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.