The number of proliferating cells in treated Ts65Dn mice underwent an increase (+ 40%) in comparison with their untreated counterparts and, although this effect was only marginally significant, the number of BrdU-positive cells became similar to that of untreated euploid mice (Fig. 5 c).
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The flavonoid 7,8-DHF fosters prenatal brain proliferation potency in a mouse model of Down syndrome.
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