Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy.

Nat Commun · 2021 · PMC7985512 · PMID 33753741

Europe PMC DOI

hedged sentence

0.2460

closest p · 4.9× alpha

0.2460

boldest claim

The sentences

did not reach statistical significancep = 0.246not close (p > 0.1)

Whereas the analysis revealed a moderate correlation of NfL with AACS-graded motoric dysfunction in AMN patients (Spearman’s r = 0.376), the average increase of 4.6% in NfL levels with each additional AACS-motor function grading point did not reach statistical significance ( p = 0.246; Supplementary Fig. 7 ).

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