Barely Significant
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Polychlorinated biphenyls altered gut microbiome in CAR and PXR knockout mice exhibiting toxicant-associated steatohepatitis.

Toxicol Rep · 2021 · PMC7985695 · PMID 33777700

Europe PMCDOI
1
hedged sentence
0.0580
closest p · 1.2× alpha
0.0580
boldest claim

The sentences

showed a trendp = 0.058so close (0.05 < p ≤ 0.1)
In terms of gene expression related to lipid and glucose metabolism genes, Bacteroidetes and Actinobacteria showed strong positive correlations with gene expression of Fasn (fatty acid synthase, fatty acid synthesis) and Pck1 (phosphoenolpyruvate carboxykinase, gluconeogenesis) while TM7 was positively correlated with hepatic Fasn and showed a trend ( p = 0.058) for positive correlations with hepatic expression of IL-6 , Pck1 and Ppara (peroxisome-proliferator activated receptor alpha, fatty acid oxidation).

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