Pre- and Postoperative Circulating IGF-I, IGFBP-3, and IGFBP-7 Levels in Relation to Endocrine Treatment and Breast Cancer Recurrence: A Nested Case-Control Study.

Front Oncol · 2021 · PMC7986849 · PMID 33767994

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did not reach statistical significanceno p-value reported

The interaction between circulating IGFBP-7 and activated tumor-specific IGFIR/InsR, analyzed in a previous study ( 27 ), was of lower magnitude and did not reach statistical significance (data not shown).

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of borderline significanceno p-value reported

The trend was of borderline significance for IGF-I, T1:REF, T2 OR:1.6, T3 OR: 2.2 adjusted P trend =0.057 and significant for IGFBP-3 T1:REF, T2 OR:1.2, T3 OR: 2.1 adjusted P trend =0.042.

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