In the last few years, a clear trend to highly selective and sensitive screening by LC-HRMS/MS with QTOF or QOT analyzers was observed [ 19 – 21 ], particularly since hundreds of so-called new psychoactive substances (NPS) appeared on the drugs of abuse market per year [ 2 – 6 , 12 , 22 ].
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Hyphenated high-resolution mass spectrometry-the "all-in-one" device in analytical toxicology?
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