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The European Medicines Agency review of entrectinib for the treatment of adult or paediatric patients with solid tumours who have a neurotrophic tyrosine receptor kinase gene fusions and adult patients with non-small-cell lung cancer harbouring ROS1 rearrangements.

ESMO Open · 2021 · PMC7988279 · PMID 33735800

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showed a trendno p-value reported
QT prolongation) or showed a trend towards reversibility (e.g. skin, liver and hematopoietic toxic effects) upon entrectinib discontinuation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.