Elevated interleukin-6 levels are associated with impaired outcome in cardiac transthyretin amyloidosis.

World J Cardiol · 2021 · PMC7988596 · PMID 33791079

Europe PMC DOI

hedged sentences

0.0490

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

borderline significantP = 0.049actually significant

Dividing our cohort according to the established cutoff for cTnT of 50 ng/mL identified in the groups with cTnT negative group a prognostic separation for death/htx endpoint ( P = 0.02) and a borderline significant prognostic separation for MACE ( P = 0.049).

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a clear trendP = 0.052so close (0.05 < p ≤ 0.1)

In patients with elevated NTproBNP levels (above 450 ng/mL[ 24 - 26 ]), high IL-6 levels were significantly associated htx/death ( P = 0.01) and a clear trend for increased incidence of MACE could be observed ( P = 0.052).

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