Chronic Kidney Disease-Induced Vascular Calcification Impairs Bone Metabolism.

However, bone resorption as indicated histomorphometrically by the erodic surface did not differ between the three groups, although a nonsignificant trend toward a higher number of osteoclasts was found in the uremic ATx rats.

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However, there was a distinct trend toward an increased adjusted apposition rate in the uremic ATx group versus normal ATx and control groups, which, however, did not reach statistical significance due to the large biological variability within the uremic ATx group (Fig. 5 F ).

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