Low-Dose Tamoxifen Induces Significant Bone Formation in Mice.

JBMR Plus · 2021 · PMC7990151 · PMID 33778320

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Other osteoblast genes also showed a trend toward increased expression, but only achieved significance at the highest TAM dose: +166% for Alp ( p < 0.0001), +223% for Bglap ( p < 0.0001), and +228% for Sp7 ( p < 0.0001) compared to control (Fig. 4 D ).

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