The proliferation curve of mAb 3.1-treated macrophages was different from the isotype control at 1.25 μg/well (Holm–Sidak post hoc test) and showed a trend of significant activity at 3.75 and 7.5 μg/well (differences were only significant with a Fisher post hoc test).
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A blocking antibody against canine CSF-1R maturated by limited CDR mutagenesis.
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