Barely Significant
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Self-buffering capacity of a human sulfatase for central nervous system delivery.

Sci Rep · 2021 · PMC7991414 · PMID 33762621

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quite significantno p-value reported
This inherent self-buffering capacity could be quite significant at high protein concentrations and has been reported to be sufficient to maintain long term and/or accelerated stability of several antibody drugs 5 – 8 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.