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Therapies with CCL25 require controlled release via microparticles to avoid strong inflammatory reactions.

J Nanobiotechnology · 2021 · PMC7992824 · PMID 33766057

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M0-polarized macrophages also increased expression of HLA-DR after supernatant stimulation from either CL or NL particles, but did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.