Mutant IDH and non-mutant chondrosarcomas display distinct cellular metabolomes.

Cancer Metab · 2021 · PMC7992867 · PMID 33762012

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showed a trendno p-value reported

Fumarate is replenished by phenylalanine and tyrosine, both of which are amino acids elevated in IDH mutant chondrosarcomas, and malate is derived from pyruvate, an organic acid which also showed a trend for increase in mutant IDH chondrosarcomas.

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