YH12852, a Potent and Selective Receptor Agonist of 5-hydroxytryptamine, Increased Gastrointestinal Motility in Healthy Volunteers and Patients With Functional Constipation.

Likewise, the sensation of incomplete evacuation during bowel movement was decreased after YH12852, particularly at 1.0–3.0 mg, and this decrease was numerically greater than in the placebo group, although it failed to reach statistical significance ( Figure 2c ).

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