Two distinct conformers of PrP<sup>D</sup> type 1 of sporadic Creutzfeldt-Jakob disease with codon 129VV genotype faithfully propagate in vivo.

Acta Neuropathol Commun · 2021 · PMC7995586 · PMID 33766126

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did not reach statistical significanceno p-value reported

In the cerebellum, astrogliosis also was significantly more severe than that observed in mice inoculated with T1 variants (Additional file 3 : Figure S3 C and E) although granule cell depopulation did not reach statistical significance (Additional file 3 : Figure S3D and E).

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