Flow cytometry Flow cytometry performed on tumor samples from mice sacrificed at day 14 revealed that the percentage of tumor-infiltrating CD8 + T cells in animals treated with dual axis inhibition trended higher than the percentage in either the control or the mono anti-PD-1 group, but this difference did not reach statistical significance (27.4 vs. 19.05 and 19.70; p > 0.05).
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Co-inhibitor expression on tumor infiltrating and splenic lymphocytes after dual checkpoint inhibition in a microsatellite stable model of colorectal cancer.
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