Introduction It is approximated that 250 million people worldwide suffer from osteoarthritis (OA), with an increasing trend in prevalence during the last decades, which continues to rise [ 1 , 2 , 3 ].
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Comprehensive Review of Knee Osteoarthritis Pharmacological Treatment and the Latest Professional Societies' Guidelines.
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They did, however, note that the observed cartilage quality did not reach statistical significance in the analyzed studies.