Germline Variation in <i>PDCD1</i> Is Associated with Overall Survival in Patients with Metastatic Melanoma Treated with Anti-PD-1 Monotherapy.

Cancers (Basel) · 2021 · PMC8002987 · PMID 33803602

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

showed a trendp = 0.060so close (0.05 < p ≤ 0.1)

In univariable analyses, germline variation in GZMB and PDCD1 showed a trend towards associations with OS according to the dominant model (HR 1.811, 95%CI 0.945–3.364, p = 0.060 and HR 2.027, 95%CI 0.998–4.118, p = 0.051, respectively).

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