Myocardial expression of somatotropic axis, adrenergic signalling, and calcium handling genes in heart failure with preserved ejection fraction and heart failure with reduced ejection fraction.

ESC Heart Fail · 2021 · PMC8006736 · PMID 33512777

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showed a trendno p-value reported

ADRB1 expression showed a trend to decrease (~24%), although not significant, in HFrEF (0.66 ± 0.4) when compared with controls (0.86 ± 0.4), while ADRB2 expression levels were comparable between HFrEF (0.65 ± 0.3) and controls (0.68 ± 0.1).

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