HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner.

However, while we detected no differences in the expression of ATG16L1 ( Figure 3C ; blue lines), we found a ~ 2-fold reduction in LC3B mRNA in Nef-expressing cells, although it did not reach statistical significance ( Figure 3C , green lines).

also in 111,027 other papers