As expected, alpha-diversity for the three studied groups was higher than for negative controls, although it did not reach statistical significance for post-treatment samples (Fig. 1 A–C).
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Esophageal microbiome in active eosinophilic esophagitis and changes induced by different therapies.
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The sentences
When post-treatment samples were also classified according to therapy, a significant reduction in inverse Simpson’s ( p = 0.049) index was detected in paired t-test exclusively for samples from patients treated with a FED, while p -values were close to significance for Chao1 and Shannon’s H indices (0.056 and 0.075, respectively) (Fig. 1 D–F).