Moreover, qRT-PCR analysis of AXIN1 and JUNB, genes belonging to WNT and β-Catenin Gene Sets, respectively, confirmed their down-regulation, although they did not reach statistical significance ( P = 0.11 and 0.099, respectively; Fig S4E ).
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The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets.
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