Adenovirus-vectored T cell vaccine for hepacivirus shows reduced effectiveness against a CD8 T cell escape variant in rats.

PLoS Pathog · 2021 · PMC8009437 · PMID 33735321

Europe PMC DOI

hedged sentence

0.0995

closest p · 2.0× alpha

0.0995

boldest claim

The sentences

marginally insignificantp = 0.0995so close (0.05 < p ≤ 0.1)

a clear trendno p-value reported

Despite a clear trend towards diminished immunity against escape virus (64% vs 25%), the difference in infection outcome between challenge groups was marginally insignificant ( Fig 3E ; p = 0.0995).

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