nominally significantp < 0.05
On the other hand, among the 986 SNPs with estimated PPR >99%, 47% were nominally significant with p < 0.05 in the replication cohort 23andMe, and 79% with consistent direction of effects.
On the other hand, among the 986 SNPs with estimated PPR >99%, 47% were nominally significant with p < 0.05 in the replication cohort 23andMe, and 79% with consistent direction of effects.
This SNP was highly significant as an outlier in one cohort, but became insignificant when meta-analyzed using the rest of the cohorts (Fixed Effects PVALUE=0.6).