Pharmacological Interventions to Treat Antipsychotic-Induced Dyslipidemia in Schizophrenia Patients: A Systematic Review and Meta Analysis.

Off Label Lipid Lowering Agents: Others For other off label lipid lowering agents, there was a statistically significant reduction in total cholesterol levels ( Figure 6 ; N = 27, n = 1,322; WMD = −5.18 mg/dL, CI: −10.31, −0.05; p = 0.05; I 2 = 41) along with a decreasing trend in levels of triglycerides that was nonsignificant ( Figure 2 ; N = 28, n = 1,337; WMD = −11.06, CI: −23.08, 0.97; p = 0.07; I 2 = 39).

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Total PANSS scores showed a trend toward improvement in the intervention group, but the difference again was not statistically significant ( Supplementary Figure 8 ; N = 13, n = 1,005, WMD = −2.15; CI: −4.45, 0.16; p = 0.07).

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