Following treatment with bevacizumab, changes in FMISO TNR showed a correlation with progression free and overall survival, although this did not reach statistical significance.
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Evaluation of <sup>18</sup>F-FMISO PET and <sup>18</sup>F-FDG PET Scans in Assessing the Therapeutic Response of Patients With Metastatic Colorectal Cancer Treated With Anti-Angiogenic Therapy.
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However, the survival curves for the post-treatment FMISO TNR did demonstrate a trend towards significance, with p-value of 0.16 for PFS and 0.14 for OS ( Figures 4A, B ).