Likewise, high-volume COVID-19 centers (−22.7%; 95%CI, −23.7 to −21.8) had greater reductions in stroke hospitalization volumes than mid- (−19.8%; 95%CI, −20.8 to −19.0; p < 0.0001) and low-volume (−12.6%; 95%CI, −13.4 to −11.9; p < 0.0001) COVID-19 centers, Table 1 . Changes in stroke care metrics during the pandemic as a function of stroke center MT and admission volumes Significant declines in the mean monthly volumes were observed for all stroke/MT metrics across low-, mid-, and high-volume stroke/MT centers except MT volumes in low-volume MT centers showed a trend in decline ( Tables 1 , 2 , S4, and S5).
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