Pfs230 yields higher malaria transmission-blocking vaccine activity than Pfs25 in humans but not mice.

This effect was not observed with high-dose vaccine, where Pfs25 showed a trend to lower antibody levels after coadministration of the 2 vaccines ( Figure 2G compared with Figure 2B, P = 0.12), and there was no effect of vaccine combinations on anti-Pfs230 responses ( Figure 2, H and I ).

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