Efficacy and safety of vancomycin loading doses in critically ill patients with methicillin-resistant <i>Staphylococcus aureus</i> infection.

Ther Adv Infect Dis · 2021 · PMC8013631 · PMID 33854772

Europe PMC DOI

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0.0560

closest p · 1.1× alpha

0.0560

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The sentences

did not reach statistical significancep = 0.056so close (0.05 < p ≤ 0.1)

The first serum vancomycin trough concentration was slightly higher in the loading dose group, but this did not reach statistical significance [15.6 (11.0–24.4) μg/ml versus 14.0 (9.5–21.0) μg/ml; p = 0.056].

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