showed a trendP = 0.09
In the post-hoc analysis, the differences between the slopes for the lead-in period and the follow-up were significant at 12 months for intrathecal, P = 0.025 and showed a trend for intraspinal, P = 0.09.
In the post-hoc analysis, the differences between the slopes for the lead-in period and the follow-up were significant at 12 months for intrathecal, P = 0.025 and showed a trend for intraspinal, P = 0.09.
Overall, MSC administration did not have a significant effect on ALSFRS-R decline rate, but with highly significant subgroup differences at all times examined.