While we found that levels of inhibitory synaptic density in the thalamic VPM/VPL regions exhibited a strong trend towards a sex-dependent phenotype in both Grn +/+ and Grn R493X/R493X mice (Additional file 1 : Fig.
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Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice.
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