Sequestosome-1 (p62) expression reveals chaperone-assisted selective autophagy in immune-mediated necrotizing myopathies.

Though we did not identify any significant difference in the gene expression of p62 or LC3 when comparing the V+ and V− IMNM groups, we did see significantly more p62 + and LC3 + myofibers in biopsies harboring vacuoles (V+) as compared to biopsies without vacuoles (V−) even though this did not reach statistical significance.

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