Fore versus hind gait symmetry (the ratio of forelimb stepping frequency to hind limb stepping frequency) tended to vary between the genotypes, but this effect did not reach statistical significance ( P = 0.061) (Figure 4C ).
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Aged Tmem106b knockout mice display gait deficits in coincidence with Purkinje cell loss and only limited signs of non-motor dysfunction.
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0.0610
0.0610