only marginally significantP = 0.044
Inversely, haplotype AGA was significantly associated with a higher risk of severe acne vulgaris in male patients (OR = 1.822, P = 0.002), and haplotype AGA also affected risk in the whole patient group, but the P value was only marginally significant (OR = 1.350, P = 0.044), and this positive association disappeared after Bonferroni correction.