Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk.

JCI Insight · 2021 · PMC8021115 · PMID 33591955

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did not reach statistical significanceno p-value reported

There was a consistent trend toward lower fasting blood glucose levels (AAV-ACY1 [149.8 ± 5.71 mg/dL] versus AAV-GFP [162.4 ± 4.21 mg/dL]; P = 0.11; Figure 6F ), although this did not reach statistical significance — perhaps due to chronic increases in insulin levels and subsequent compensatory pathways.

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highly significantno p-value reported

We identified dozens of markers with highly significant associations with future T2DM across 2 large longitudinal cohorts ( n = 2839) followed for up to 16 years.

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