We found that EPZ-6438 or P5091 alone showed a trend in reducing tumor growth as compared to vehicle treatment, albeit not statistically significant, whereas their combination significantly reduced tumor growth ( P < 0.05) ( Fig. 7, G to I ).
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Posttranslational regulation of FOXA1 by Polycomb and BUB3/USP7 deubiquitin complex in prostate cancer.
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