When comparing the Fulton index of LysM-Cre Pdgfb fl/fl with that of Pdgfb fl/fl mice, there was a trend toward reduction with hypoxia and increase with normoxia, but these differences did not reach statistical significance ( Figure 2E ).
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Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension.
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