a significant trendp < 0.0001
For all the kits tested, there was a significant trend of increasing methylation levels with a severity of the disease (Cuzick tests for trend, p < 0.0001, Figure 6 .).
For all the kits tested, there was a significant trend of increasing methylation levels with a severity of the disease (Cuzick tests for trend, p < 0.0001, Figure 6 .).